hrp0084p3-949 | GH & IGF | ESPE2015

Plexiform Neurofibroma and Demielinisant Lesions in a Patient with GH Deficiency Treated with rGH

Cima Luminita-Nicoleta , Albu Alice , Fica Simona , Barbu Carmen Gabriela

Case report: A 13-year old boy treated with rGH for short stature due to isolated GH deficiency was submitted in our clinic in June 2014 for regular follow-up. From his medical history we note that he was diagnosed with GH deficiency in 2009 (−4.5 S.D.) and started treatment with rGH 0.035 mg/kgc per day since February 2009. The physical exam showed H=149.9 cm (−0.74 S.D.), 39 kg, Tanner P3G3 and a subcutaneous left paravertebral tumou...

hrp0092p1-202 | Fat, Metabolism and Obesity (1) | ESPE2019

Visceral Adiposity Index as a Marker of Metabolic Risk in Survivors of Paediatric Hematopoietic Stem Cell Transplantation After Chemotherapy-Only Conditioning

Cima Luminita-Nicoleta , Nedelea Lavinia , Soare Iulia , Barbu Carmen Gabriela , Zaharia Cristina , Colita Anca , Fica Simona

Background: Hematopoietic stem cell transplantation (HSCT) recipients exhibit excess adiposity that may result in an increased metabolic risk. Studies have shown that BMI is a poor predictor of body fatness in pediatric HSCT survivors population where diminished lean mass has been documented. The visceral adiposity index (VAI) has recently been proposed as a predictor of cardio-metabolic risk in both adults and children. However, the predictive value of this i...

hrp0089lb-p11 | Late Breaking P1 | ESPE2018

Metabolic Profile in Survivors of Pediatric Hematopoietic Stem Cells Transplantation after Chemotherapy-Only Conditioning

Cima Luminita-Nicoleta , Nedelea Lavinia , Zaharia Cristina , Colita Anca , Barbu Carmen Gabriela , Fica Simona

Background: Metabolic syndrome (MS) is a long-term complication of pediatric haematopoietic stem cell transplantation (HSCT) and it was described more often in patients who were exposed to total body irradiation (TBI). Since previous studies reported discrepancy in the presence of metabolic complications in HSCT survivors who underwent chemotherapy-only conditioning, we investigated the frequency of MS in our HSCT-treated children for various disorders without being exposed to...

hrp0086p2-p940 | Thyroid P2 | ESPE2016

An Unusual Case of Impaired Renal Function and Thrombocytopenia

Cima Luminita Nicoleta , Lungu Adrian , Ionescu Bogdan , Lambrescu Ioana Maria , Barbu Carmen Gabriela , Fica Simona

Background: Autoimmune thyroid disease can be sometimes associated with autoimmune thrombocytopenia and decreased renal function.Case report: A 17-year-old female patient was referred to our endocrine department for evaluation of hypothyroidism (TSH=150 mcIU/ml, FT3=0 pg/ml, FT4<0.1 ng/dl) presenting severe fatigability and myalgia. From her medical history we mention that she was diagnosed with thrombocytopenia 1 year ago (85.000/mm...

hrp0097p1-585 | Thyroid | ESPE2023

Papillary thyroid carcinoma incidentally discovered in young patients - a case series

Grosu Iustina , Dumitrache Sabina-Maria , Zubaci Ana , Stan Raluca , Cima Luminita-Nicoleta , Vasilache Simona , Martin Sorina-Carmen , Sirbu Anca-Elena , Soare Iulia , Barbu Carmen-Gabriela , Miron Adrian , Terzea Dana , Fica Simona

Introduction: Thyroid carcinoma in pediatric and young adult population presents contradictory features: it has higher rates of multifocal disease, local and distant metastasis and reccurence compared to the adult population, yet the 5-year survival rate is 98%. The rising incidence seen recently cannot be entirely explained by overdiagnosis, as increasing rates of advanced-stage disease are also observed. The rise consists primarily of papillary thyroid carci...